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The following publications are some of the most recent research articles published by researchers at The Cooper Institute.
L DeFina, B Willis, N Radford, A Gao, D Leonard, W Haskell, M Weiner, and J Berry. The relation between mid-life cardiorespiratory fitness and later-life dementia. Annals of Internal Medicine, 2013;158:162-168.
Higher midlife fitness levels seem to be associated with lower hazards of developing all-cause dementia later in life. The magnitude and direction of the association were similar with or without previous stroke, suggesting that higher fitness levels earlier in life may lower risk for dementia later in life, independent of cerebrovascular disease.
B Willis, A Gao, D Leonard, L DeFina, J Berry. Midlife fitness and the development of chronic conditions in later life. Archives Internal Medicine, 2012;172(17):1333-1340.
In this cohort of healthy middle-aged adults, fitness was significantly associated with a lower risk of developing chronic disease outcomes during 26 years of follow-up. These findings suggest that higher midlife fitness may be associated with the compression of morbidity in older age.
S. Farrell, C Finley, and S. Grundy. Cardiorespiratory fitness, LDL cholesterol, and CHD mortality in men. Med Sci Sports Exerc, 2012;44(11):2132-2137.
PMID 22776869.
This study examined the associations among cardiorespiratory fitness, LDL cholesterol, and risk of death from coronary heart disease (CHD) in 40,718 men who were examined at the Cooper Clinic between 1971 and 2006. A total of 557 deaths from coronary heart disease occurred during an average follow-up period of 16.7 years. Compared with men who had a low level of fitness, at a moderate to high level of fitness, the risk of CHD death within each of 5 categories of LDL cholesterol was significantly reduced. This study suggests that measurement of cardiorespiratory fitness should be considered for routine cardiovascular risk assessment and management.
K Shuval, C Finley, K Chartier, B Balasubramanian, K Pettee Gabriel, C Barlow. Cardiorespiratory fitness, alcohol consumption, and metabolic syndrome incidence in men. Med Sci Sports Exercise,2012;44(11):2125-2131.
Among this cohort of men, higher fitness levels reduced the risk for MetS and its components. The relation between alcohol intake levels and metabolic risk was more complex and not reflected when examining MetS as a whole.
N Beasley, S Sharma, R Shegog, R Huber, P Abernathy, C Smith, D Hoelscher. The Quest to Lava Mountain: Using video games for dietary change in children. J Academy of Nutrition and Dietetics, 2012;112:1334-1336.
J Morrow, L DeFina, D Leonard, E Trudelle-Jackson, M Custodio. Meeting physical activity guidelines and musculoskeletal injury: The WIN Study. Med Sci Sports Exerc, 2012;44:1986-1992.
The results illustrate the risk of MSI with PA. MSI risk rises with increasing PA. Despite this modest increase in MSIs, the known benefits of aerobic and resistance PAs should not hinder physicians from encouraging patients to meet current PAGs for both moderate-to-vigorous exercise and RE behaviors with the intent of achieving health benefits.
J Bachmann, B Willis, C Ayers, A Khera, J Berry. Association between family history and coronary heart disease death across long-term follow-up in men: The CCLS. Circulation, 2012;125:3092-3098.
Premature family history was associated with a persistent increase in both CHD and CVD mortality risk across long-term follow-up, resulting in significantly higher lifetime risk estimates.
P Gu, L DeFina, D Leonard, S John, M Weiner, S Brown. Relationship between serum homocysteine levels and depressive symptoms: The Cooper Center Longitudinal Study. J Clinical Psychiatry, 2012;73(5):691-695.
PMID: 22480447
This study examined the relationship between serum HCY levels and depressive symptoms in 11,757 participants (69% men) aged 20 - 90 years who completed preventive health examinations at the Cooper Clinic from 2007 – 2010. Currently experiencing depression was defined as a score of ≥10 on the 10-item Center for Epidemiologic Studies Depression Scale. After controlling for several other mediating factors, elevated HCY was associated with 26% greater odds of depressive symptoms.
C Hoehner, C Barlow, P Allen, M Schootman. Commuting distance, cardiorespiratory fitness, and metabolic risk. American J Preventive Medicine, 2012;42(6):571-578.
This study examined the association between commuting distance, physical activity, cardiorespiratory fitness, and metabolic risk indicators. This cross-sectional study included ~4300 adults who had a comprehensive examination at the Cooper Clinic between 2000-2007 and geocoded home and work addresses in 12 Texas metropolitan counties. Commuting distance was adversely associated with physical activity, cardiorespiratory fitness, adiposity, and indicators of metabolic risk.
PMID: 22608372
K Cooper. The benefits of exercise in promoting long and healthy lives – My observations. Methodist DeBakey Cardiovascular Journal, 2010;VI(4):10-12.
K Shuval, C Barlow, K Chartier, K Pettee Gabriel. Cardiorespiratory fitness, alcohol, and mortality in men: The CCLS. Am J Preventive Medicine, 2012;42(5):460-467.
PMID: 22516485
This study examined the independent and joint effects of alcohol consumption and cardiorespiratory fitness on all-cause and cardiovascular mortality in 29,402 men in the Cooper Center Longitudinal Study. 1830 deaths (all-cause) and 523 (cardiovascular) deaths occurred. Examining the joint effects of fitness and alcohol consumption showed that moderate and high levels of fitness were protective for all-cause mortality.
S Grundy, C Barlow, S Farrell, G Vega, W Haskell. Cardiorespiratory fitness and metabolic risk. Am J Cardiology, 2012;109:988-993. E-pub Nov 2011.
PMID: 22221951
This study evaluated the relation between cardiovascular risk factors and cardiorespiratory fitness, determined by maximal exercise testing, in 59,820 men and 22,192 women in the Cooper Center Longitudinal Study. With decreasing cardiorespiratory fitness, increases occurred in obesity, triglycerides, non-high-density lipoprotein cholesterol, triglyceride / high-density lipoprotein ratios, blood pressure, metabolic syndrome, diabetes, and cigarette smoking. Physical activity, self-reported, declined with decreasing levels of cardiorespiratory fitness.
R Vigen, C Ayers, B Willis, L DeFina, J Berry. Association of cardiorespiratory fitness with total, cardiovascular, and noncardiovascular mortality across 3 decades of follow-up in men and women. Circulation Cardiovascular Quality and Outcomes. 2012;5(3):358-364.
PMID: 22474246
The pattern of the association between low fitness and mortality across short- (0-10 years), intermediate- (10 – 20 years), and long-term (>20 years) follow-up was studied in 46,575 men and 16,151 women in the Cooper Center Longitudinal Study. Low fitness was associated with all-cause mortality and cardiovascular and noncardiovascular disease deaths across all periods in men and women.
S Farrell, B Willis. Cardiorespiratory fitness, adiposity, and serum 25-dihydroxyvitamin D levels in women. J Women’s Health, 2012;21(1):80-86. E-pub Oct 2011.
PMID: 21970522
M Mathew, J Morrow, G Frierson, T Bain. Assessing digital literacy in web-based physical activity surveillance: The WIN Study. Am J Health Promotion, 2011;26:90-95.
PMID: 22040389
MT Hoang, L DeFina, B Willis, D Leonard, M Weiner, E Brown. Association between low serum 25-hydroxyvitamin D and depression in a large sample of healthy adults: The Cooper Center Longitudinal Study. Mayo Clinic Proceedings, 2011;86(11):1050-1055.
PMID: 22033249
B Willis, J Morrow, A Jackson, L DeFina, K Cooper. Secular change in cardiorespiratory fitness of men: CCLS. Medicine and Science in Sports and Exercise, 2011;43:2134-2139.
PMID: 21448076
H Chambliss, R Huber, C Finley, S McDoniel, H Kitzman-Ulrich, W Wilkinson. Computerized self-monitoring and technology-assisted feedback for weight loss with and without an enhanced behavioral component. Patient Education and Counseling, 2011;85:375-382.
PMID: 21295433
E Trudelle-Jackson, A Jackson, J Morrow, Jr. Relations of meeting national public health recommendations for muscular strengthening activities with strength, body composition, and obesity: The WIN Study. American J Public Health, 2011101:1930-1935.
PMID: 21852647
E Trudelle-Jackson, E Ferro, J Morrow. Clinical implications for muscle strength differences in women of different age and racial groups: The WIN Study. J Women’s Health Physical Therapy, 2011;35(1):11-18.
S Farrell, C Finley, P McAuley, G Frierson. Cardiorespiratory fitness, different measures of adiposity, and total cancer mortality in women. Obesity, 2011;19:2261-2267. e-pub Feb 2011.
PMID: 21293448
S. Farrell, C. Finley, P. McAuley, G. Frierson. Cardiorespiratory Fitness, Different Measures of Adiposity, and Total Cancer Mortality in Women. Obesity. Feb 3, 2011 (epub ahead of print).
PMID: 21293448
S Lakoski, C Barlow, S Farrell, J Berry, J Morrow, W Haskell. Impact of body mass index, physical activity, and other clinical factors on cardiorespiratory fitness: The CCLS. American J Cardiology, 2011;108:34-39.
PMID: 21529738
J Berry, B Willis, S Gupta, C Barlow, S Lakoski, A Khera, A Rohatgi, J de Lemos, W Haskell, D Lloyd-Jones. Lifetime risks for cardiovascular disease mortality by cardiorespiratory fitness levels measured at ages 45, 55, and 65 years in men: The CCLS. J American College Cardiology, 2011;57:1604-1610.
PMID: 21474041
S Gupta, A Rohatgi, C Ayers, B Willis, W Haskell, A Khera, M Drazner, J de Lemos, J Berry. Cardiorespiratory fitness and classification of risk of cardiovascular disease mortality. Circulation, 2011;123:1377-1383.
PMID: 21422392
L DeFina, L Marcoux, S Devers, J Cleaver, B Willis. Effects of omega-3 supplementation in combination with diet and exercise on weight loss and body composition. American J Clinical Nutrition, 2011;93:455-462.
PMID: 21159785
Farrell SW, Cleaver JP, Willis BL.
Cardiorespiratory fitness, adiposity, and serum 25-dihydroxyvitamin d levels in men. Med Sci Sports Exerc. 2011 Feb;43(2):266-71.
PMID: 20581717
I Bernstein, L Lacritz, C Barlow, M Weiner, L DeFina.
Psychometric evaluation of the Montreal Cognitive Assessment in three diverse samples. The Clinical Neuropsychologist, 2011;25:119-126.
PMID: 21154110
J Ho, C Barlow, D Reinhardt, W Wade, J Cannaday. Effect of increasing body mass index on image quality and positive predictive value of 100-kV coronary computed tomographic angiography. American J Cardiology, 2010;106:1182-1186.
PMID: 20920661
C East, B Willis, C Barlow, B Grannemann, S FitzGerald, L DeFina, M Trivedi. Depressive symptoms and metabolic syndrome in preventive healthcare: The CCLS. Metabolic Syndrome and Related Disorders, 2010;8(5):451-457.
PMID: 20854094
C Finley, B Wright, T Haltom, W Haskell.
Glycemic index, glycemic load, and prevalence of the metabolic syndrome in the Cooper Center Longitudinal Study. J American Dietetic Association, 2010;110:1820-1829.
PMID: 21111092
B Massoudi, M Olmsted, Y Zhang, R Carpenter, C Barlow, R Huber.
A web-based intervention to support increased physical activity among at-risk adults. J of Biomedical Informatics, 2010;43:S41-S45.
PMID: 20696275
J Morrow, T Bain, G Frierson, E Trudelle-Jackson, W Haskell.
Long-term tracking of physical activity behaviors in women: The WIN Study. Medicine and Science in Sports and Exercise, 2010;43:165-170.
PMID: 20473221
S Beckham, M Harper.
Functional training: Fad or here to stay? ACSM’s Health & Fitness Journal, 2010;14(6):24-30.
Farrell S, Fitzgerald S, McAuley P, and Barlow C.
Cardiorespiratory Fitness, Adiposity, and all-cause Mortality in Women. Medicine and Science in Sports and Exercise. 2010;42(11):2006-2012.
PMID: 20351588
Texas Youth Fitness Study. Supplement to Research Quarterly for Exercise and Sport. Editors: SB Martin, JR Morrow, Jr. 2010;81:ii-S83. The Supplement is composed of the 11 papers listed below from the statewide fitness testing in Texas on almost 3 million children per year beginning in 2007. The analyses, evaluation, and interpretation of the data and the publication of the Supplement were funded by the Robert Wood Johnson Foundation.
KH Cooper, D Everett, MD Meredith, J Kloster, M Rathbone, K Read.
Preface: Texas Statewide Assessment of Youth Fitness.
PMID: 21049831
JR Morrow, Jr, SB Martin, GJ Welk, W Zhu, MD Meredith.
Overview of the Texas Youth Fitness Study.
PMID: 21049832
GJ Welk, MD Meredith, M Ihmels, C Seeger.
Distribution of Health-Related Physical Fitness in Texas Youth: A Demographic and Geographic Analysis.
PMID: 21049833
GJ Welk, AW Jackson, JR Morrow, Jr, WH Haskell, MD Meredith, KH Cooper.
The Association of Health-Related Fitness with Indicators of Academic Performance in Texas Schools.
PMID: 21049834
JR Morrow, Jr, SB Martin, AW Jackson.
Reliability and Validity of the FITNESSGRAM®: Quality of Teacher-Collected Health-Related Fitness Surveillance Data.
PMID: 21049835
SB Martin, A Ede, JR Morrow, Jr, AW Jackson.
Statewide Physical Fitness Testing: Perspectives from the Gym.
PMID: 21049836
W Zhu, GJ Welk, MD Meredith, EA Boiarskaia.
A Survey of Physical Education Programs and Policies in Texas Schools.
PMID: 21049837
W Zhu, EA Boiarskaia, GJ Welk, MD Meredith.
Physical Education and School Contextual Factors Relating to Students’ Achievement and Cross-Grade Differences in Aerobic Fitness and Obesity.
PMID: 21049838
CA Greenleaf, TA Petrie, SB Martin.
Psychosocial Variables Associated with Body Composition and Cardiorespiratory Fitness in Middle School Students.
PMID: 21049839
CB Corbin.
Texas Youth Fitness Study: A Commentary.
PMID: 21049840
KH Cooper.
Reflections on the Texas Youth Evaluation Project and Implications for the Future.
PMID: 21049841
G Vega, C Barlow, S Grundy.
Prevalence of the metabolic syndrome as influenced by the measure of obesity employed.
Am J Cardiology, 2010;105:1306-1312.
PMID: 20403484
JS Ho, JJ Cannaday, CE Barlow, BL Willis, WL Haskell, SJ FitzGerald.
Comparative relation of general, central, and visceral adiposity measures for coronary artery calcium in subjects without previous coronary events.
Am J Cardiology, 2009;104:943-946.
PMID: 20084008
JS Ho, SJ FitzGerald, CE Barlow, JJ Cannaday, HW Kohl, WL Haskell, KH Cooper.
Risk of mortality increases with increasing number of abnormal non-ST parameters recorded during exercise testing. Eur J Cardiovascular and Prevention Rehabilitation, 2010;17:462-468.
TM Bain, GM Frierson, E Trudelle-Jackson, JR Morrow, Jr.
Internet reporting of weekly physical activity behaviors: The Win Study.
J Physical Activity and Health, 2010;7:527-532.
PMID: 20683095
E Trudelle-Jackson, LA Fleisher, N Borman, JR Morrow, Jr, GM Frierson.
Lumbar spine flexion and extension extremes of motion in women of different age and racial groups: The WIN Study. Spine, 2010;35(16):1539-1544.
PMID: 20072092
J Chen, S Das, CE Barlow, S Grundy, SG Lakoski.
Fitness, fatness, and systolic blood pressure: Data from the CCLS.
Am Heart J, 2010;160:166-170.
PMID: 20598988
C Xing, J Cohen, E Boerwinkle.
A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels. Am J Human Genetics, 2010;86:440–446.
PMID: 20152958
CY Wang, WL Haskell, SW Farrell, MJ LaMonte, SN Blair, LR Curtin, JP Hughes, VL Burt. Cardiorespiratory fitness levels among US adults 20-49 years of age: Findings from the 1999-2004 National Health and Nutrition Examination Study (NHANES).
Am J Epidemiology, 2010;171:426-435.
PMID: 2008080
